Talk:Agent Orange

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Higher Ground 1[edit]

To Higher Ground 1: Please discuss, rather than edit war. Why do you insist on adding this image as well as unsourced content? Chris Troutman (talk) 19:53, 23 February 2018 (UTC)

Before/after image problems[edit]

Under the section "Ecological impact" the image of the mangrove forest purports to be a before/after image but they are clearly not images of the same location. Maybe they are just demonstrative of the *type* of impact caused but labelling it as before/after implies it is an apples to apples comparison, which it isn't. mmj (talk) 23:56, 9 April 2018 (UTC)

Mechanism of action? Time of effect? Duration?[edit]

A lot of focus on the impact but no focus on the underlying biochemistry. - Keith D. Tyler 20:33, 7 February 2019 (UTC)

A person pictured with birth deformities (short arms) appears to have Holt-Oram syndrome[edit]

The person pictured with arm deformities appears to have Holt-Oram syndrome,[1] a genetic condition caused by mutations of the TBX5 gene, or other similar pseudo-thalidomide syndrome. The condition is very likely not Dioxin related. It also important to understand that Dioxin (TCDD and dioxin related compounds) cause congenital malformations by binding with the Aryl hydrocarbon cell receptor (AhR), this in turn induces or mimics dietary folate deficiency. Accordingly, congenital malformations caused by dioxin are theoretically limited neural tube defects only e.g. cleft lip/pallet, spina bifida, encephalocele, iniencephaly and anencephaly. We can use this information to decide if a congenital deformity is likely dioxin relayed or not. -- Diamonddavej (talk) 01:09, 22 February 2019 (UTC)